Skip to main content

Two medicines, side by side

Betamethasone vs triamcinolone

Betamethasone and triamcinolone are both labeled for asthma, eczema (atopic dermatitis), leukemia, lymphoma and myeloma and anemia. Drugs@FDA records approvals of betamethasone since 1961 and of triamcinolone since 1957. Pharmacies paid $0.418 per gram (Betamethasone dp 0.05% cream) and $0.0452 per gram (Triamcinolone 0.1% cream) (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like. Triamcinolone's other strengths are brand-only: $2.33 per mL (Kenalog-10 50 mg/5 mL vial).

Check it at the source: the betamethasone FDA label on DailyMed (effective January 28, 2026); the triamcinolone FDA label on DailyMed (effective January 28, 2026).

Highlights of the betamethasone record

Betamethasone (Celestone) · label of January 28, 2026

Used for

From the label: indications

Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

On the market

Earliest approval on file
April 17, 1961
Generic labelers
28 labelers
Pharmacy cost
$0.418 per gram

Supply and safety

Shortage
No current entry
Recalls
13

Highlights of the triamcinolone record

Triamcinolone (Kenalog) · label of January 28, 2026

Used for

From the label: indications

Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

On the market

Earliest approval on file
December 3, 1957
Generic labelers
73 labelers
Pharmacy cost
$0.0452 per gram

Supply and safety

Shortage
Listed; available
Recalls
27

Source: FDA drug labels via openFDA (Betamethasone label of January 28, 2026, Triamcinolone label of January 28, 2026); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do betamethasone and triamcinolone differ on the record?

Both are in FDA's class corticosteroids.

Generics: betamethasone since 1979; triamcinolone since 1972 (Drugs@FDA).

BetamethasoneTriamcinolone
Labeled forAsthma, Eczema (atopic dermatitis), Anemia, Leukemia, lymphoma and myeloma, Multiple sclerosis, PsoriasisAsthma, Eczema (atopic dermatitis), Anemia, Leukemia, lymphoma and myeloma, Allergies, Fever, Pain, Osteoarthritis
Pharmacologic classCorticosteroidCorticosteroid
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)April 17, 1961December 3, 1957
First generic approvedJanuary 30, 1979April 26, 1972
Generic labelers (NDC)28 labelers73 labelers
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.418 per gram (Betamethasone dp 0.05% cream)$0.0452 per gram (Triamcinolone 0.1% cream)
12-month price change-23%-18%
Boxed warningNoNo
Shortage nowNo current entryListed; available
Recalls recorded1327
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)10,81231,591
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to betamethasone
every medicine labeled for the same conditions