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azilsartan vs lithium

Side-by-side comparison of azilsartan and lithium. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

moderate Known Drug Interaction

7 DRUG INTERACTIONS Renal clearance of lithium is reduced by diuretics, such as chlorthalidone increasing the risk of lithium toxicity ( 7 ) NSAIDS increase risk of renal dysfunction and interfere with antihypertensive effect ( 7 ) Dual inhibition of the renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia ( 7 ) Lithium: Increases in serum lithium concentrations and lithium toxicity ( 7 ) 7.1 Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) In patients who are elderly, volume-depleted (including...

Recommendation: Your doctor should monitor your lithium blood levels closely. They may need to adjust your lithium dose while you are taking this medication.

Drug Class
azilsartan Angiotensin II Receptor Blocker (ARB)
lithium Mood Stabilizer
Type
azilsartan Prescription
lithium Prescription
Summary
azilsartan

No summary available.

lithium

Lithium is a mood stabilizer medicine. It helps to balance mood swings.

What It Treats
azilsartan

Information not available.

lithium

Lithium is used to treat bipolar disorder. Bipolar disorder causes unusual shifts in mood, energy, activity levels, and concentration. Lithium helps to control the extreme highs (mania) and lows (depression) of this condition.

How It Works
azilsartan

Information not available.

lithium

Lithium affects the flow of sodium in nerve and muscle cells in the body. This helps to stabilize your mood. It may also affect other chemical messenger systems in the brain.

Common Side Effects
azilsartan
  • Dizziness
  • Fatigue
lithium
  • Tremor (shaking)
  • Nausea
  • Increased weight
  • Fatigue (feeling tired)
  • Vomiting
FAERS Reports
azilsartan

No adverse event reports.

lithium
  • Poisoning from different substances 2,179
  • The drug is reacting with another medicine 1,526
  • Shaking 1,463
  • Feeling sick to your stomach 1,344
  • Gaining weight 1,153
Serious Warnings
azilsartan

No specific warnings noted.

lithium

Lithium levels in your blood need to be monitored closely by your doctor. Too much lithium can be toxic and cause serious side effects. Make sure to attend all scheduled blood tests.

Pregnancy
azilsartan

No pregnancy information available.

lithium

Lithium can harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Lithium can pass into breast milk and may harm a nursing infant. Talk to your doctor about the best way to feed your baby if you are taking lithium.

Also Compare, Nearby Drugs

How to Read This azilsartan vs lithium Comparison

azilsartan is classified in the Angiotensin II Receptor Blocker (ARB) drug class, while lithium sits within the Mood Stabilizer class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, azilsartan has 0 submissions while lithium has 7,665. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to azilsartan can make it harder for the kidneys to remove lithium from the body. this causes lithium levels to build up, which can lead to dangerous side effects.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between azilsartan and lithium - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.