atorvastatin vs phenytoin
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Side-by-side comparison of atorvastatin and phenytoin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Warfarin Increased and decreased PT/INR responses have been reported when phenytoin is coadministered with warfarin Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Antiepileptic drugs a Carbamazepine, felbamate, lamotrigine, topiramate, oxcarbazepine Antilipidemic agents Atorvastatin, fluvastatin, simvastatin Antiviral agents Efavirenz, lopinavir/ritonavir, indinavir, nelfinavir, ritonavir, saquinavir Fosamprenavir: phenytoin when given with...
Lipitor
Dilantin
Atorvastatin is a drug that lowers cholesterol and reduces the risk of heart problems and stroke. It belongs to a class of drugs called statins.
Phenytoin injection is used to treat certain types of seizures. It can also prevent seizures during or after neurosurgery.
Atorvastatin is used to lower bad cholesterol (LDL) and triglycerides in your blood. It can help prevent heart attacks, strokes, and the need for heart procedures in adults with heart disease or risk factors for it. It is also used in children 10 years and older with certain inherited cholesterol problems.
This medicine treats generalized tonic-clonic status epilepticus, a type of prolonged seizure. It also helps prevent and treat seizures that may happen during or after brain surgery. Sometimes, it can be used for a short time instead of the oral form of phenytoin when you cannot take the medicine by mouth.
Atorvastatin works by blocking a substance your body needs to make cholesterol. This helps to lower the amount of cholesterol in your blood. Lowering cholesterol can help prevent heart disease.
Phenytoin works by slowing down the signals in the brain that cause seizures. It stabilizes nerve cell membranes, reducing excessive electrical activity. This helps to prevent seizures from starting or spreading.
- • Common cold symptoms
- • Joint pain
- • Diarrhea
- • Pain in arms or legs
- • Urinary tract infection
No common side effects listed.
- Fatigue 13,812
- Nausea 12,425
- Type 2 Diabetes Mellitus 11,244
- Diarrhoea 11,037
- Dyspnoea 11,029
- Drug Interaction 1,547
- Seizure 1,382
- Toxicity To Various Agents 1,353
- Convulsion 1,262
- Status Epilepticus 791
Atorvastatin can cause muscle problems, including muscle pain, tenderness, or weakness. In rare cases, this can lead to serious kidney damage. Tell your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or feel sick. Atorvastatin can also cause liver problems. Your doctor may do blood tests to check your liver before you start taking atorvastatin and while you are taking it.
This medicine can cause serious heart problems if given too quickly. The injection rate should not be faster than 50 mg per minute for adults, and 1 to 3 mg/kg/min (or 50 mg per minute, whichever is slower) for children. Your heart will be monitored closely during and after the injection.
Atorvastatin can harm an unborn baby. You should not take atorvastatin if you are pregnant or planning to become pregnant. It is also not recommended to breastfeed while taking atorvastatin.
Taking phenytoin during pregnancy may increase the risk of birth defects. If you are pregnant or plan to become pregnant, talk to your doctor about the risks and benefits of this medicine.
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How to Read This atorvastatin vs phenytoin Comparison
atorvastatin is classified in the HMG-CoA Reductase Inhibitor (Statin) drug class, while phenytoin sits within the Anticonvulsant (Hydantoin) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, atorvastatin has 59,547 submissions while phenytoin has 6,335. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to phenytoin speeds up the process of clearing atorvastatin from your body. this results in lower levels of the cholesterol medicine in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for atorvastatin or phenytoin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.