amiodarone vs lovastatin
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Side-by-side comparison of amiodarone and lovastatin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
Amiodarone The risk of myopathy/rhabdomyolysis is increased when amiodarone is used concomitantly with a closely related member of the HMG-CoA reductase inhibitor class (see WARNINGS , Myopathy/Rhabdomyolysis ).
Cordarone, Pacerone
Mevacor, Altoprev
Amiodarone (Pacerone) is a medicine used to treat life-threatening, irregular heartbeats. It helps to restore a normal heart rhythm when other medicines don't work or can't be used.
Lovastatin is a medicine that helps lower cholesterol levels in your blood. It belongs to a class of drugs called statins.
This medicine treats very fast, irregular heartbeats in the ventricles (lower chambers of the heart). It is used when these irregular heartbeats are life-threatening. It is also used when other medicines don't work well enough or cause too many side effects. This medicine is for adults.
Lovastatin is used to lower cholesterol and reduce the risk of heart problems. It can help prevent heart attacks, unstable angina (chest pain), and the need for procedures to open blocked arteries. It's also used to slow down the hardening of arteries in people who already have heart disease. Lovastatin can also be used in children 10-17 years of age with high cholesterol due to genetic causes.
Amiodarone affects the electrical signals in your heart. It slows down these signals, which helps your heart beat normally. This medicine can help prevent dangerous, fast heart rhythms.
Lovastatin works by blocking a substance your body needs to make cholesterol. This helps to lower the amount of cholesterol in your blood. Lowering cholesterol helps to prevent heart disease and stroke.
- • Low thyroid levels (hypothyroidism)
- • High thyroid levels (hyperthyroidism)
- • Heart failure
- • Irregular heartbeats
- • Problems with the heart's natural pacemaker (SA node dysfunction)
- • Abdominal pain
- • Constipation
- • Diarrhea
- • Gas
- • Nausea
- Dyspnoea 1,158
- Asthenia 975
- Fatigue 895
- Nausea 606
- Cough 597
- Fatigue 1,518
- Nausea 1,396
- Diarrhoea 1,251
- Dyspnoea 1,209
- Dizziness 1,147
This medicine can cause serious problems with your lungs, liver, and heart. Lung problems can be fatal. Your doctor will check your lungs with X-rays and breathing tests. Liver problems can also be fatal. Your doctor will check your liver with blood tests. This medicine can also make irregular heartbeats worse. You will likely start this medicine in the hospital where your heart can be monitored.
Lovastatin can cause muscle problems, including muscle breakdown (rhabdomyolysis), which can lead to kidney damage. The risk is higher if you take certain other medicines with lovastatin. You should not take lovastatin if you have liver problems or are pregnant or breastfeeding.
This medicine can harm your unborn baby. It can cause thyroid problems, slow heart rate, and brain development issues. Do not breastfeed while taking this medicine.
You should not take lovastatin if you are pregnant or breastfeeding. It can harm your unborn baby. If you are a woman who could become pregnant, use effective birth control while taking lovastatin.
Also Compare, Nearby Drugs
Compare amiodarone with
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How to Read This amiodarone vs lovastatin Comparison
amiodarone is classified in the Class III Antiarrhythmic drug class, while lovastatin sits within the HMG-CoA Reductase Inhibitor (Statin) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amiodarone has 4,231 submissions while lovastatin has 6,521. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to taking amiodarone with lovastatin makes it harder for your body to process the cholesterol drug. this can lead to a buildup of lovastatin that may damage your muscles.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for amiodarone or lovastatin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.