amikacin vs cefixime
Side-by-side comparison of amikacin and cefixime Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Amikacin is an antibiotic medicine. It fights serious infections caused by certain types of bacteria.
Cefixime is an antibiotic that fights bacteria in your body. It is used to treat several different types of bacterial infections.
Amikacin treats serious infections caused by bacteria. This includes infections in the blood, lungs, bones, joints, brain, skin, and abdomen. It can also treat burns, post-surgery infections, and complicated urinary tract infections.
Cefixime treats infections like urinary tract infections, ear infections, and sore throats. It also treats bronchitis and gonorrhea. This medicine should only be used to treat infections that are proven or very likely to be caused by bacteria. This helps to prevent bacteria from becoming resistant to the medicine.
Amikacin belongs to a class of drugs called aminoglycosides. It works by stopping the growth of bacteria. This helps your body fight off the infection.
Cefixime belongs to a class of drugs called cephalosporins. It works by stopping the growth of bacteria. This helps your body fight off the infection.
No common side effects listed.
- • Diarrhea (16%)
- • Nausea (7%)
- • Loose stools (6%)
- • Abdominal pain (3%)
- • Indigestion (3%)
- Off Label Use 1,908
- Drug Ineffective 1,673
- Cough 1,620
- Dyspnoea 1,556
- Hospitalisation 1,360
- Drug Ineffective 276
- Off Label Use 268
- Pyrexia 162
- Nausea 155
- Diarrhoea 150
Amikacin can potentially cause hearing loss and kidney damage. Tell your doctor if you have kidney problems or are taking other medicines that can affect your hearing or kidneys. Your doctor should closely monitor you for hearing and kidney problems during treatment. This drug can also cause muscle weakness or breathing problems, especially if you are also taking anesthesia or certain muscle relaxants.
Cefixime can cause severe allergic reactions, including shock and death. Stop taking cefixime and get medical help right away if you have any signs of an allergic reaction. Cefixime can also cause severe diarrhea due to a bacteria called Clostridium difficile. Tell your doctor right away if you have diarrhea while taking cefixime.
Tell your doctor if you are pregnant or breastfeeding. Amikacin may harm your unborn baby. It is not known if amikacin passes into breast milk.
Tell your doctor if you are pregnant or plan to become pregnant. Studies haven't shown harm to the fetus, but it's important to discuss the risks and benefits with your doctor. It is not known whether cefixime passes into breast milk.
Also Compare — Nearby Drugs
Compare amikacin with
Compare cefixime with
How to Read This amikacin vs cefixime Comparison
amikacin is classified in the Aminoglycoside Antibiotic drug class, while cefixime sits within the Third-Generation Cephalosporin class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amikacin has 8,117 submissions while cefixime has 1,011. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between amikacin and cefixime — always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.