alogliptin vs cimetidine
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Side-by-side comparison of alogliptin and cimetidine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
( 7 ) Drugs that reduce metformin clearance (such as ranolazine, vandetanib, dolutegravir, and cimetidine), may increase the accumulation of metformin. Examples: Ranolazine, vandetanib, dolutegravir, and cimetidine Alcohol Clinical Impact: Alcohol is known to potentiate the effect of metformin on lactate metabolism.
Nesina
Tagamet
No summary available.
Cimetidine (Tagamet) reduces stomach acid. It is used to treat ulcers, heartburn, and other conditions where too much acid is produced.
Information not available.
Cimetidine treats active duodenal ulcers for short periods. It can also be used long-term at a lower dose to prevent ulcers from returning. This medicine also treats active benign gastric ulcers for a short time. Additionally, it can help with erosive gastroesophageal reflux disease (GERD), which damages the esophagus.
Information not available.
Cimetidine is an H2 receptor antagonist. This means it blocks histamine from attaching to certain cells in your stomach. By blocking histamine, cimetidine reduces the amount of acid your stomach makes.
- • Upper respiratory tract infection
- • Common cold
- • Diarrhea
- • High blood pressure
- • Headache
- • Headache
- • Dizziness
- • Diarrhea
- Diarrhoea 134
- Nausea 124
- Vomiting 110
- Acute Kidney Injury 101
- Pemphigoid 101
- Chronic Kidney Disease 1,264
- Acute Kidney Injury 710
- Renal Failure 694
- Nausea 681
- Fatigue 598
No specific warnings noted.
Reversible confusional states (like mental confusion, agitation, or hallucinations) have been reported, mostly in severely ill patients. These usually appear within 2-3 days of starting treatment and clear up within 3-4 days of stopping the drug.
No pregnancy information available.
Tell your doctor if you are pregnant or plan to become pregnant. The effects of cimetidine during pregnancy are not fully known. Talk to your doctor about the risks and benefits of taking cimetidine while breastfeeding.
Also Compare, Nearby Drugs
Compare alogliptin with
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How to Read This alogliptin vs cimetidine Comparison
alogliptin is classified in the DPP-4 Inhibitor drug class, while cimetidine sits within the H2 Receptor Antagonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, alogliptin has 570 submissions while cimetidine has 3,947. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to cimetidine can slow down how the body removes the medication, which may lead to the drug building up in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for alogliptin or cimetidine.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.