Two medicines, side by side
Alfuzosin vs amoxicillin
Alfuzosin is labeled for enlarged prostate (bph); amoxicillin for bacterial infections and acid reflux and ulcers. Their labels share no use, so they are not alternatives to each other. Drugs@FDA records approvals of alfuzosin since 2003 and of amoxicillin since 1974. Pharmacies paid $0.105 per alfuzosin HCl ER 10 mg tablet and $0.0788 per amoxicillin 500 mg capsule (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like. In FDA's classes, alfuzosin is an alpha-adrenergic blocker and amoxicillin a penicillin-class antibacterial.
Check it at the source: the alfuzosin FDA label on DailyMed (effective December 5, 2024); the amoxicillin FDA label on DailyMed (effective February 22, 2024).
Highlights of the alfuzosin record
Alfuzosin (Uroxatral) · label of December 5, 2024
Used for
From the label: indicationsUROXATRAL is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. UROXATRAL is an alpha adrenergic antagonist, indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. ( 1 ) Important Limitations of Use: UROXATRAL is not indicated for treatment of hypertension. ( 1.1 ) UROXATRAL is not indicated for use in the pediatric population. […]
On the market
- Earliest approval on file
- June 12, 2003
- Generic labelers
- 10 labelers
- Pharmacy cost
- $0.105 per tablet
Supply and safety
- Shortage
- No current entry
- Recalls
- 1
Highlights of the amoxicillin record
Amoxicillin (Amoxil) · label of February 22, 2024
Used for
From the label: indicationsAdults and Pediatric Patients • Upper Respiratory Tract Infections of the Ear, Nose, and Throat Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus species. (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp. , or Haemophilus influenzae. […]
On the market
- Earliest approval on file
- January 18, 1974
- Generic labelers
- 38 labelers
- Pharmacy cost
- $0.0788 per capsule
Supply and safety
- Shortage
- No current entry
- Recalls
- 12
Source: FDA drug labels via openFDA (Alfuzosin label of December 5, 2024, Amoxicillin label of February 22, 2024); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)
How do alfuzosin and amoxicillin differ on the record?
In FDA's classes, alfuzosin is an alpha-adrenergic blocker and amoxicillin a penicillin-class antibacterial.
How each works, in its label's words: Alfuzosin, “Alfuzosin is a selective antagonist of post-synaptic alpha 1 -adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.”; Amoxicillin, “Amoxicillin is an antibacterial drug [see Microbiology ( 12.4 )].”
Half-life, in each label's words: Alfuzosin, “Following oral administration of UROXATRAL 10 mg tablets, the apparent elimination half-life is 10 hours.”; Amoxicillin, “Metabolism and Excretion The half-life of amoxicillin is 61.3 minutes.”
Generics: alfuzosin since 2011; amoxicillin since 1974 (Drugs@FDA).
| Alfuzosin | Amoxicillin | |
|---|---|---|
| Labeled for | Enlarged prostate (BPH) | Bacterial infections, Acid reflux and ulcers |
| Pharmacologic class | alpha-Adrenergic Blocker | Penicillin-class Antibacterial |
| How it works (label) | Alfuzosin is a selective antagonist of post-synaptic alpha 1 -adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra. | Amoxicillin is an antibacterial drug [see Microbiology ( 12.4 )]. |
| Half-life (label) | Following oral administration of UROXATRAL 10 mg tablets, the apparent elimination half-life is 10 hours. | Metabolism and Excretion The half-life of amoxicillin is 61.3 minutes. |
| Earliest approval on file (Drugs@FDA) | June 12, 2003 | January 18, 1974 |
| First generic approved | July 18, 2011 | December 9, 1974 |
| Generic labelers (NDC) | 10 labelers | 38 labelers |
| Pharmacy cost (NADAC, each one's most listed form; strengths differ) | $0.105 per tablet (Alfuzosin HCl ER 10 mg tablet) | $0.0788 per capsule (Amoxicillin 500 mg capsule) |
| 12-month price change | -0.1% | -12% |
| Boxed warning | No | No |
| Shortage now | No current entry | No current entry |
| Recalls recorded | 1 | 12 |
| FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used) | 5,746 | 75,926 |
| DEA schedule | none | none |
Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)
What next?
- Alternatives to alfuzosin
- every medicine labeled for the same conditions