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Two medicines, side by side

Albuterol vs amoxicillin

Albuterol is labeled for asthma; amoxicillin for bacterial infections and acid reflux and ulcers. Their labels share no use, so they are not alternatives to each other. Drugs@FDA records approvals of albuterol since 1981 and of amoxicillin since 1974. Pharmacies paid $0.288 per albuterol sulfate 2 mg tablet and $0.0788 per amoxicillin 500 mg capsule (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like. In FDA's classes, albuterol is a beta2-adrenergic agonist and amoxicillin a penicillin-class antibacterial.

Check it at the source: the albuterol FDA label on DailyMed (effective April 30, 2026); the amoxicillin FDA label on DailyMed (effective February 22, 2024).

Highlights of the albuterol record

Albuterol (Ventolin) · label of April 30, 2026

Used for

From the label: indications

Albuterol Inhalation Solution is indicated for the relief of bronchospasm in patients 2 to 12 years of age with asthma (reversible obstructive airway disease).

On the market

Earliest approval on file
May 1, 1981
Generic labelers
40 labelers
Pharmacy cost
$0.288 per tablet

Supply and safety

Shortage
Resolved
Recalls
20

Highlights of the amoxicillin record

Amoxicillin (Amoxil) · label of February 22, 2024

Used for

From the label: indications

Adults and Pediatric Patients • Upper Respiratory Tract Infections of the Ear, Nose, and Throat Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus species. (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp. , or Haemophilus influenzae. […]

On the market

Earliest approval on file
January 18, 1974
Generic labelers
38 labelers
Pharmacy cost
$0.0788 per capsule

Supply and safety

Shortage
No current entry
Recalls
12

Source: FDA drug labels via openFDA (Albuterol label of April 30, 2026, Amoxicillin label of February 22, 2024); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do albuterol and amoxicillin differ on the record?

In FDA's classes, albuterol is a beta2-adrenergic agonist and amoxicillin a penicillin-class antibacterial.

Generics: albuterol since 1989; amoxicillin since 1974 (Drugs@FDA).

AlbuterolAmoxicillin
Labeled forAsthmaBacterial infections, Acid reflux and ulcers
Pharmacologic classbeta2-Adrenergic AgonistPenicillin-class Antibacterial
How it works (label)n/aAmoxicillin is an antibacterial drug [see Microbiology ( 12.4 )].
Half-life (label)n/aMetabolism and Excretion The half-life of amoxicillin is 61.3 minutes.
Earliest approval on file (Drugs@FDA)May 1, 1981January 18, 1974
First generic approvedJanuary 30, 1989December 9, 1974
Generic labelers (NDC)40 labelers38 labelers
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.288 per tablet (Albuterol sulfate 2 mg tablet)$0.0788 per capsule (Amoxicillin 500 mg capsule)
12-month price change-38%-12%
Boxed warningNoNo
Shortage nowResolvedNo current entry
Recalls recorded2012
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)292,13675,926
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to albuterol
every medicine labeled for the same conditions