FDA pharmacologic class
Transthyretin-directed RNA Interaction
3 medicines are in FDA's class of transthyretin-directed rna interactions: eplontersen (Wainua), patisiran (Onpattro) and vutrisiran (Amvuttra). 0 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are transthyretin-directed rna interaction?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Eplontersen | Wainua | none listed | n/a | No | No current entry | 0 |
| Patisiran | Onpattro | none listed | n/a | No | No current entry | 0 |
| Vutrisiran | Amvuttra | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)