FDA pharmacologic class
Progestin-containing Intrauterine System
1 medicine is in FDA's class of progestin-containing intrauterine systems: levonorgestrel (Plan); 2 combination products also contain one. 2 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is falmina-28 tablet at $0.154 per tablet (NADAC).
Which medicines are progestin-containing intrauterine system?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Levonorgestrel | Plan, Mirena, Kyleena | 31 labelers | $6.33 per tablet 1.5 mg tablet | No | No current entry | 3 |
| Ethinyl estradiol and levonorgestrel | Twirla, Tyblume, Balcoltra | 19 labelers | $0.154 per tablet 28 tablet | Yes | No current entry | 9 |
| Estradiol and levonorgestrel | Climara | none listed | $59.64 per patch Climara pro patch | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price