FDA pharmacologic class
Plasma Kallikrein Inhibitor
4 medicines are in FDA's class of plasma kallikrein inhibitors: berotralstat (Orladeyo), lanadelumab (Takhzyro), ecallantide (Kalbitor) and sebetralstat (Ekterly). 0 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are plasma kallikrein inhibitor?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Berotralstat | Orladeyo | none listed | n/a | No | No current entry | 0 |
| Lanadelumab | Takhzyro | none listed | n/a | No | No current entry | 0 |
| Ecallantide | Kalbitor | none listed | n/a | Yes | No current entry | 1 |
| Sebetralstat | Ekterly | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)