FDA pharmacologic class
Peroxisome Proliferator Receptor alpha Agonist
4 medicines are in FDA's class of peroxisome proliferator receptor alpha agonists: fenofibrate (Tricor), pioglitazone (Actos), gemfibrozil (Lopid) and fenofibric acid; 3 combination products also contain one. 5 of the 7 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is pioglitazone hcl 15 mg tablet at $0.0675 per tablet (NADAC).
Which medicines are peroxisome proliferator receptor alpha agonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Fenofibrate | Antara, Lipofen, Tricor | 54 labelers | $0.103 per tablet 160 mg tablet | No | No current entry | 8 |
| Pioglitazone | Actos | 22 labelers | $0.0675 per tablet 15 mg tablet | Yes | No current entry | 2 |
| Gemfibrozil | Lopid | 27 labelers | $0.104 per tablet 600 mg tablet | Yes | A presentation being discontinued | 0 |
| Fenofibric acid | none listed | 7 labelers | $0.286 per capsule 135 mg capsule | No | No current entry | 4 |
| Metformin and pioglitazone | Actoplus | 5 labelers | $0.283 per unit 15-500 | Yes | No current entry | 1 |
| Alogliptin and pioglitazone | Oseni | none listed | $4.73 per tablet 25-15 mg tablet | Yes | No current entry | 0 |
| Glimepiride and pioglitazone | Duetact | none listed | $10.52 per unit 30-4 | Yes | No current entry | 1 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price