FDA pharmacologic class
Partial opioid agonists
1 medicine is in FDA's class of partial opioid agonists (partial opioid agonists): buprenorphine (Belbuca); 1 combination product also contains one. All 2 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is buprenorphine 2 mg tablet sl at $0.277 per tablet (NADAC).
Which medicines are partial opioid agonists?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Buprenorphine | Belbuca, Brixadi, Butrans | 27 labelers | $0.277 per tablet 2 mg tablet sl | No | No current entry | 12 |
| Buprenorphine and naloxone | Zubsolv, Suboxone | 26 labelers | $0.521 per tablet 2-0.5 mg sl tablet | No | No current entry | 2 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price