FDA pharmacologic class
Melatonin Receptor Agonist
2 medicines are in FDA's class of melatonin receptor agonists: ramelteon (Rozerem) and tasimelteon (Hetlioz). All 2 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is ramelteon 8 mg tablet at $0.660 per tablet (NADAC).
Which medicines are melatonin receptor agonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Ramelteon | Rozerem | 27 labelers | $0.660 per tablet 8 mg tablet | No | A presentation being discontinued | 0 |
| Tasimelteon | Hetlioz | 3 labelers | $228.25 per capsule 20 mg capsule | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price