FDA pharmacologic class
Leukocyte Growth Factor
5 medicines are in FDA's class of leukocyte growth factors: filgrastim (Neupogen), pegfilgrastim (Neulasta), eflapegrastim (Rolvedon), efbemalenograstim alfa (Ryzneuta) and sargramostim (Leukine). 0 of the 5 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is neupogen 300 mcg/0.5 ml syringe at $650.05 per mL (NADAC).
Which medicines are leukocyte growth factor?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Filgrastim | Nypozi, Neupogen, Releuko | none listed | $650.05 per mL 300 mcg/0.5 mL syringe | No | No current entry | 3 |
| Pegfilgrastim | Udenyca, Neulasta, Stimufend | none listed | $3,369.51 per mL 6 mg/0.6 mL syringe | No | No current entry | 1 |
| Eflapegrastim | Rolvedon | none listed | n/a | No | No current entry | 0 |
| Efbemalenograstim alfa | Ryzneuta | none listed | n/a | No | No current entry | 0 |
| Sargramostim | Leukine | none listed | n/a | No | No current entry | 1 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price