FDA pharmacologic class
Interleukin-6 Receptor Antagonist
2 medicines are in FDA's class of interleukin-6 receptor antagonists: tocilizumab (Actemra) and sarilumab (Kevzara). 0 of the 2 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is tyenne 162 mg/0.9 ml autoinjct at $821.00 per mL (NADAC).
Which medicines are interleukin-6 receptor antagonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Tocilizumab | Tyenne, Tofidence, Actemra | none listed | $821.00 per mL 162 mg/0.9 mL autoinjct | Yes | No current entry | 1 |
| Sarilumab | Kevzara | none listed | $2,075.30 per mL 200 mg/1.14 mL pen injection | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price