FDA pharmacologic class
Hydrolytic Lysosomal Glycogen-specific Enzyme
3 medicines are in FDA's class of hydrolytic lysosomal glycogen-specific enzymes: alglucosidase alfa (Lumizyme), avalglucosidase alfa (Nexviazyme) and cipaglucosidase alfa (Pombiliti). 0 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are hydrolytic lysosomal glycogen-specific enzyme?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Alglucosidase alfa | Lumizyme | none listed | n/a | Yes | No current entry | 1 |
| Avalglucosidase alfa | Nexviazyme | none listed | n/a | Yes | No current entry | 0 |
| Cipaglucosidase alfa | Pombiliti | none listed | n/a | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)