FDA pharmacologic class
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
5 medicines are in FDA's class of human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitors: etravirine (Intelence), nevirapine, efavirenz, rilpivirine (Edurant) and doravirine (Pifeltro); 7 combination products also contain one. 7 of the 12 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is nevirapine 200 mg tablet at $0.147 per tablet (NADAC).
Which medicines are human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Etravirine | Intelence | 5 labelers | $9.94 per tablet 200 mg tablet | No | A presentation being discontinued | 0 |
| Nevirapine | none listed | 6 labelers | $0.147 per tablet 200 mg tablet | Yes | No current entry | 1 |
| Efavirenz | none listed | 5 labelers | $1.28 per tablet 600 mg tablet | No | No current entry | 0 |
| Efavirenz and emtricitabine and tenofovir disoproxil | none listed | 7 labelers | $1.12 per tablet 600-200-300 mg tablet | Yes | No current entry | 0 |
| Rilpivirine | Edurant | 2 labelers | $48.04 per tablet 25 mg tablet | No | No current entry | 0 |
| Efavirenz and lamivudine and tenofovir disoproxil | Symfi | 1 labeler | n/a | Yes | No current entry | 0 |
| Emtricitabine and rilpivirine and tenofovir disoproxil | Complera | 2 labelers | $114.50 per tablet 200-25-300 mg tablet | Yes | No current entry | 0 |
| Doravirine | Pifeltro | none listed | $60.79 per tablet 100 mg tablet | No | No current entry | 0 |
| Dolutegravir and rilpivirine | Juluca | none listed | $121.87 per tablet 50-25 mg tablet | No | No current entry | 0 |
| Doravirine and islatravir | Idvynso | none listed | n/a | No | No current entry | 0 |
| Doravirine and lamivudine and tenofovir disoproxil | Delstrigo | none listed | $93.06 per tablet 100-300-300 mg tablet | Yes | No current entry | 0 |
| Emtricitabine and rilpivirine and tenofovir alafenamide | Odefsey | none listed | $130.49 per tablet Odefsey tablet | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price