FDA pharmacologic class
Histone Deacetylase Inhibitor
4 medicines are in FDA's class of histone deacetylase inhibitors: romidepsin (Istodax), belinostat (Beleodaq), givinostat (Duvyzat) and vorinostat (Zolinza). 1 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are histone deacetylase inhibitor?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Romidepsin | Istodax | 2 labelers | n/a | No | No current entry | 0 |
| Belinostat | Beleodaq | none listed | n/a | No | No current entry | 0 |
| Givinostat | Duvyzat | none listed | n/a | No | No current entry | 0 |
| Vorinostat | Zolinza | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)