FDA pharmacologic class
Gonadotropin Releasing Hormone Receptor Antagonist
3 medicines are in FDA's class of gonadotropin releasing hormone receptor antagonists: ganirelix (Fyremadel), elagolix (Orilissa) and relugolix (Orgovyx); 1 combination product also contains one. 1 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is orilissa 150 mg tablet at $43.81 per tablet (NADAC).
Which medicines are gonadotropin releasing hormone receptor antagonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Ganirelix | Fyremadel | 9 labelers | $62.35 per mL 250 mcg/0.5 mL | No | No current entry | 3 |
| Elagolix | Orilissa | none listed | $43.81 per tablet 150 mg tablet | No | No current entry | 1 |
| Estradiol and norethindrone and relugolix | Myfembree | none listed | $45.25 per tablet 40 mg-1 mg-0.5 mg tablet | Yes | No current entry | 0 |
| Relugolix | Orgovyx | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price