FDA pharmacologic class
Gadolinium-based Contrast Agent
4 medicines are in FDA's class of gadolinium-based contrast agents: gadobutrol (Gadavist), gadoterate (Dotarem), gadobenate (Multihance) and gadoxetate (Eovist). 2 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are gadolinium-based contrast agent?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Gadobutrol | Gadavist | 4 labelers | n/a | Yes | A presentation being discontinued | 0 |
| Gadoterate | Dotarem, Clariscan | 3 labelers | n/a | Yes | A presentation being discontinued | 0 |
| Gadobenate | Multihance | none listed | n/a | Yes | No current entry | 2 |
| Gadoxetate | Eovist | none listed | n/a | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)