FDA pharmacologic class
Factor Xa inhibitors
4 medicines are in FDA's class of factor Xa inhibitors (factor Xa inhibitors): rivaroxaban (Xarelto), fondaparinux (Arixtra), apixaban (Eliquis) and edoxaban (Savaysa). 3 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is rivaroxaban 2.5 mg tablet at $0.650 per tablet (NADAC).
Which medicines are factor xa inhibitors?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Rivaroxaban | Xarelto | 20 labelers | $0.650 per tablet 2.5 mg tablet | Yes | A presentation being discontinued | 1 |
| Fondaparinux | Arixtra | 5 labelers | $44.82 per mL 10 mg/0.8 mL syringe | Yes | No current entry | 1 |
| Apixaban | Eliquis | 2 labelers | $5.52 per tablet 5 mg tablet | Yes | No current entry | 0 |
| Edoxaban | Savaysa | none listed | $15.51 per tablet 60 mg tablet | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price