FDA pharmacologic class
Ergotamine Derivative
2 medicines are in FDA's class of ergotamine derivatives: dihydroergotamine (Trudhesa) and ergotamine (Ergomar); 1 combination product also contains one. All 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is dihydroergotamine mesylate 4 mg/ml nasal spray at $29.44 per mL (NADAC).
Which medicines are ergotamine derivative?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Dihydroergotamine | Atzumi, Trudhesa, Brekiya | 9 labelers | $29.44 per mL 4 mg/mL nasal spray | Yes | No current entry | 2 |
| Caffeine and ergotamine | Cafergot, Migergot | 3 labelers | n/a | Yes | No current entry | 0 |
| Ergotamine | Ergomar | 1 labeler | $43.46 per tablet 2 mg tablet sublingual | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price