FDA pharmacologic class
Diagnostic Dye
4 medicines are in FDA's class of diagnostic dyes: fluorescein (Ak-Fluor), indocyanine green (Ic-Green), indigotindisulfonate (Bludigo) and trypan blue (Membraneblue); 1 combination product also contains one. 2 of the 5 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are diagnostic dye?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Fluorescein | Ak-Fluor | 4 labelers | n/a | No | No current entry | 1 |
| Indocyanine green | Ic-Green, Zyogreen | 2 labelers | n/a | No | No current entry | 0 |
| Benoxinate and fluorescein | Altafluor | none listed | n/a | No | No current entry | 0 |
| Indigotindisulfonate | Bludigo | none listed | n/a | No | No current entry | 0 |
| Trypan blue | Membraneblue, Visionblue | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)