FDA pharmacologic class
Cytoprotective Agent
4 medicines are in FDA's class of cytoprotective agents: dexrazoxane, bleomycin, mesna (Mesnex) and amifostine (Ethyol). 3 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is bleomycin sulfate 15 unit vial at $26.45 per vial (NADAC).
Which medicines are cytoprotective agent?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Dexrazoxane | none listed | 6 labelers | n/a | No | No current entry | 0 |
| Bleomycin | none listed | 5 labelers | $26.45 per vial 15 unit vial | Yes | No current entry | 3 |
| Mesna | Mesnex | 6 labelers | n/a | No | No current entry | 0 |
| Amifostine | Ethyol | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price