FDA pharmacologic class
Cystic Fibrosis Transmembrane Conductance Regulator Potentiator
1 medicine is in FDA's class of cystic fibrosis transmembrane conductance regulator potentiators: ivacaftor (Kalydeco); 2 combination products also contain one. 0 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are cystic fibrosis transmembrane conductance regulator potentiator?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Ivacaftor | Kalydeco | none listed | n/a | No | No current entry | 0 |
| Ivacaftor and lumacaftor | Orkambi | none listed | n/a | No | No current entry | 0 |
| Deutivacaftor and tezacaftor and vanzacaftor | Alyftrek | none listed | n/a | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)