FDA pharmacologic class

Complement Inhibitor

6 medicines are in FDA's class of complement inhibitors: eculizumab (Epysqli), ravulizumab (Ultomiris), zilucoplan (Zilbrysq), pegcetacoplan (Syfovre), avacincaptad (Izervay) and pozelimab (Veopoz). 0 of the 6 are listed from generic labelers (FDA NDC Directory, October 8, 2026).

Which medicines are complement inhibitor?

Recalls: FDA enforcement reports, 2012 on
Medicine	Brand names	Generic labelers (all forms)	Pharmacy cost	Boxed warning	Shortage	Recalls since 2012
Eculizumab	Soliris, Bkemv, Epysqli	none listed	n/a	Yes	No current entry	2
Ravulizumab	Ultomiris	none listed	n/a	Yes	No current entry	0
Zilucoplan	Zilbrysq	none listed	n/a	Yes	No current entry	0
Pegcetacoplan	Empaveli, Syfovre	none listed	n/a	Yes	No current entry	0
Avacincaptad	Izervay	none listed	n/a	No	No current entry	0
Pozelimab	Veopoz	none listed	n/a	Yes	No current entry	0

Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)

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