FDA pharmacologic class
Cholinergic Receptor Agonist
6 medicines are in FDA's class of cholinergic receptor agonists: varenicline (Chantix), pilocarpine (Salagen), cevimeline (Evoxac), methacholine (Provocholine), aceclidine (Vizz) and carbachol (Miostat); 1 combination product also contains one. 3 of the 7 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is varenicline 1 mg tablet at $0.316 per tablet (NADAC).
Which medicines are cholinergic receptor agonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Varenicline | Chantix, Tyrvaya | 27 labelers | $0.316 per tablet 1 mg tablet | No | No current entry | 10 |
| Pilocarpine | Salagen, Qlosi | 7 labelers | $0.338 per tablet 5 mg tablet | No | A presentation being discontinued | 4 |
| Cevimeline | Evoxac | 13 labelers | $0.729 per capsule 30 mg capsule | No | No current entry | 1 |
| Methacholine | Provocholine | none listed | n/a | Yes | No current entry | 0 |
| Aceclidine | Vizz | none listed | n/a | No | No current entry | 0 |
| Brimonidine and carbachol | Yuvezzi | none listed | n/a | No | No current entry | 0 |
| Carbachol | Miostat | none listed | n/a | No | No current entry | 1 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price