FDA pharmacologic class
Central Nervous System Depressant
1 medicine is in FDA's class of central nervous system depressants: sodium oxybate (Xyrem); 1 combination product also contains one. 1 of the 2 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are central nervous system depressant?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Sodium oxybate | Lumryz, Xyrem | 3 labelers | n/a | Yes | A presentation being discontinued | 0 |
| Calcium oxybate, magnesium oxybate, potassium oxybate and sodium oxybate | Xywav | none listed | n/a | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)