FDA pharmacologic class
Asparagine-specific Enzyme
3 medicines are in FDA's class of asparagine-specific enzymes: asparaginase (Rylaze), calaspargase (Asparlas) and pegaspargase (Oncaspar). 0 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026).
Which medicines are asparagine-specific enzyme?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Asparaginase | Rylaze | none listed | n/a | No | No current entry | 0 |
| Calaspargase | Asparlas | none listed | n/a | No | No current entry | 0 |
| Pegaspargase | Oncaspar | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)