FDA pharmacologic class
Antimetabolite
3 medicines are in FDA's class of antimetabolites: hydroxyurea (Hydrea), floxuridine and thioguanine (Tabloid). 2 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is hydroxyurea 500 mg capsule at $0.184 per capsule (NADAC).
Which medicines are antimetabolite?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Hydroxyurea | Droxia, Hydrea, Siklos | 10 labelers | $0.184 per capsule 500 mg capsule | No | No current entry | 0 |
| Floxuridine | none listed | 3 labelers | n/a | No | No current entry | 0 |
| Thioguanine | Tabloid | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price