FDA pharmacologic class
Antidote
3 medicines are in FDA's class of antidotes: acetylcysteine (Acetadote), fomepizole and hydroxocobalamin (Cyanokit). All 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is hydroxocobalamin 1,000 mcg/ml at $0.814 per mL (NADAC).
Which medicines are antidote?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Acetylcysteine | Acetadote | 13 labelers | $2.25 per mL 20% vial (not for injection) | No | No current entry | 4 |
| Fomepizole | none listed | 6 labelers | n/a | No | No current entry | 1 |
| Hydroxocobalamin | Cyanokit | 1 labeler | $0.814 per mL 1,000 mcg/mL | No | In shortage | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price