Medicines labeled for the same conditions
Alternatives to tipiracil and trifluridine
4 other medicines are given the same way (oral) and in the same FDA class as tipiracil and trifluridine or labeled mainly for the same use (colorectal cancer); 1 is in its class, thymidine phosphorylase inhibitors: capecitabine; the others include 1 kinase inhibitor (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.456 per capecitabine 500 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as tipiracil and trifluridine?
Colorectal cancer lists all 23 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Tipiracil and trifluridinethymidine phosphorylase inhibitor | this medicine | none listed | n/a | No | No current entry |
| Capecitabinenucleoside metabolic inhibitor · same class | Colorectal cancer | 18 labelers | $0.456 per tablet 500 mg tablet | Yes | No current entry |
| Fruquintinib | Colorectal cancer | none listed | n/a | No | No current entry |
| Encorafenib | Colorectal cancer | none listed | n/a | No | No current entry |
| Regorafenibkinase inhibitor | Colorectal cancer | none listed | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Tipiracil and trifluridine: the full record
- label, generics, price, shortages, recalls