Alternatives to sulfasalazine
3 same-class SPL records vs sulfasalazine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Azulfidine
How to read a high-report FAERS peer set
sulfasalazine ranks in the upper FAERS-volume third of the corpus (#96 of 524); 3 same-class peers are listed for field comparison only. Labeled indication field for sulfasalazine: Sulfasalazine treats ulcerative colitis, a condition that causes inflammation and sores in the lining of the large intestine.
Top FAERS reaction fields for sulfasalazine total 122,091 reports across 10 reactions, set beside hydroxychloroquine, leflunomide, methotrexate. Counts are exposure-weighted submissions, not per-patient risk.
About sulfasalazine
Sulfasalazine is a drug that reduces inflammation in the body. It is used to treat ulcerative colitis.
Used for: Sulfasalazine treats ulcerative colitis, a condition that causes inflammation and sores in the lining of the large intestine. It can help with mild to moderate ulcerative colitis. It can also be used with other treatments for severe ulcerative colitis. This medicine can also help keep ulcerative colitis from coming back.
3 Disease-Modifying Antirheumatic Drug (DMARD) peers (wide set)
hydroxychloroquine
RxPlaquenil
This medicine can treat uncomplicated malaria caused by certain parasites. It can also prevent malaria in areas where the parasites are not resistant to the drug. Hydroxychloroquine also treats rheumatoid arthritis, systemic lupus erythematosus, and chronic discoid lupus erythematosus.
leflunomide
RxArava
Leflunomide treats active rheumatoid arthritis in adults. Rheumatoid arthritis is a disease that causes pain, swelling, and stiffness in the joints. This medicine can help reduce these symptoms.
methotrexate
RxTrexall, Otrexup
Methotrexate can treat acute lymphoblastic leukemia, a type of cancer, in adults and children. It also treats mycosis fungoides, a skin lymphoma, in adults. Additionally, it treats relapsed or refractory non-Hodgkin lymphoma in adults. For non-cancer conditions, it treats rheumatoid arthritis in adults, polyarticular juvenile idiopathic arthritis (pJIA) in children, and severe psoriasis in adults.
sulfasalazine vs hydroxychloroquine & leflunomide · FAERS reaction fields
FAERS top-reaction field "Arthralgia" shows the widest count spread between sulfasalazine and hydroxychloroquine, leflunomide, methotrexate in this extract (23,122-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | sulfasalazine | hydroxychloroquine | leflunomide | methotrexate |
|---|---|---|---|---|
| Rheumatoid Arthritis | 19,190 | 12,921 | 24,923 | 38,053 |
| Pain | 15,658 | 10,409 | 20,055 | 35,413 |
| Arthralgia | 13,161 | 9,276 | 16,941 | 36,283 |
| Fatigue | 13,017 | 8,853 | 15,384 | 29,061 |
| Joint Swelling | 12,481 | 8,528 | 15,567 | 22,294 |
| Rash | 10,678 | 7,370 | 13,321 | 19,771 |
| Abdominal Discomfort | 9,801 | 5,881 | 11,731 | - |
| Contraindicated Product Administered | 9,454 | 6,430 | 11,637 | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
sulfasalazine FAERS volume vs class peers
FAERS volume band
sulfasalazine is FAERS corpus rank #96 of 524 (high volume tercile). Top-reaction field total: 122,091.
Frequently Asked Questions
Where does sulfasalazine sit in FAERS report volume vs Disease-Modifying Antirheumatic Drug (DMARD) peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for sulfasalazine: see also the generic vs brand label guide when reading Azulfidine SPL strings.
Read our methodology - how this data is sourced, computed, and verified.