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Medicines labeled for the same conditions

Alternatives to sofosbuvir

3 other medicines are given the same way (oral) and in the same FDA class as sofosbuvir or labeled mainly for the same use (hepatitis c); the others include 2 hepatitis c virus ns3/4a protease inhibitors and 1 nucleoside analog antiviral (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as sofosbuvir?

Hepatitis C lists all 8 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Sofosbuvirhepatitis c virus nucleotide analog ns5b polymerase inhibitorthis medicinenone listedn/aYesNo current entry
Ribavirinnucleoside analog antiviralHepatitis C1 labeler$0.451 per tablet 200 mg tabletYesNo current entry
Glecaprevir and pibrentasvirhepatitis c virus ns3/4a protease inhibitorHepatitis Cnone listed$152.98 per tablet 100-40 mg tabletYesNo current entry
Elbasvir and grazoprevirhepatitis c virus ns3/4a protease inhibitorHepatitis Cnone listedn/aYesA presentation being discontinued

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Sofosbuvir: the full record
label, generics, price, shortages, recalls