Medicines labeled for the same conditions
Alternatives to sirolimus
6 other medicines are given the same way (oral) and in the same FDA class as sirolimus or labeled mainly for the same use (organ transplant rejection); 1 is in its class, mtor inhibitor immunosuppressants: everolimus; the others include 2 calcineurin inhibitor immunosuppressants, 2 antimetabolite immunosuppressants and 1 purine antimetabolite (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $26.32 per everolimus 10 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as sirolimus?
Organ transplant rejection lists all 13 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Sirolimusmtor inhibitor immunosuppressant | this medicine | 18 labelers | $0.723 per tablet 1 mg tablet | Yes | No current entry |
| Everolimusmtor inhibitor immunosuppressant · same class | Organ transplant rejection | 14 labelers | $26.32 per tablet 10 mg tablet | No | A presentation being discontinued |
| Tacrolimuscalcineurin inhibitor immunosuppressant | Organ transplant rejection | 30 labelers | $0.123 per capsule 0.5 mg capsule (immediate release) | Yes | No current entry |
| Mycophenolate mofetilantimetabolite immunosuppressant | Organ transplant rejection | 30 labelers | $0.138 per capsule 250 mg capsule | Yes | No current entry |
| Mycophenolic acidantimetabolite immunosuppressant | Organ transplant rejection | 16 labelers | $0.0996 per tablet 180 mg tablet | Yes | No current entry |
| Azathioprinepurine antimetabolite | Organ transplant rejection | 16 labelers | $0.124 per tablet 50 mg tablet | Yes | No current entry |
| Cyclosporinecalcineurin inhibitor immunosuppressant | Organ transplant rejection | 8 labelers | $0.314 per unit 25 mg | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Sirolimus: the full record
- label, generics, price, shortages, recalls
- Everolimus vs sirolimus
- two records side by side
- Sirolimus vs tacrolimus
- two records side by side