Medicines labeled for the same conditions
Alternatives to simvastatin
12 other medicines are given the same way (oral) and in the same FDA class as simvastatin or labeled mainly for the same use (heart attack and coronary artery disease); 7 are in its class, HMG-CoA reductase inhibitors: atorvastatin, rosuvastatin, pravastatin, amlodipine and atorvastatin and 3 more; the others include 2 adenosine triphosphate-citrate lyase inhibitors, 1 peroxisome proliferator receptor alpha agonist and 1 nicotinic acid (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0228 per atorvastatin 10 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as simvastatin?
Heart attack and coronary artery disease lists all 38 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| SimvastatinHMG-CoA reductase inhibitor | this medicine | 27 labelers | $0.0321 per tablet 20 mg tablet | No | No current entry |
| AtorvastatinHMG-CoA reductase inhibitor · same class | Heart attack and coronary artery disease, High cholesterol, High triglycerides | 61 labelers | $0.0228 per tablet 10 mg tablet | No | No current entry |
| RosuvastatinHMG-CoA reductase inhibitor · same class | Heart attack and coronary artery disease, High cholesterol, High triglycerides | 46 labelers | $0.0692 per tablet 40 mg tablet | No | No current entry |
| PravastatinHMG-CoA reductase inhibitor · same class | Heart attack and coronary artery disease, High cholesterol, High triglycerides | 37 labelers | $0.058 per tablet 20 mg tablet | No | No current entry |
| Amlodipine and atorvastatinHMG-CoA reductase inhibitor · same class | Heart attack and coronary artery disease, High cholesterol, High triglycerides | 6 labelers | $1.34 per unit 10-40 mg | No | No current entry |
| LovastatinHMG-CoA reductase inhibitor · same class | Heart attack and coronary artery disease, High cholesterol | 19 labelers | $0.0436 per tablet 20 mg tablet | No | No current entry |
| PitavastatinHMG-CoA reductase inhibitor · same class | High cholesterol | 12 labelers | $0.954 per tablet 2 mg tablet | No | No current entry |
| FluvastatinHMG-CoA reductase inhibitor · same class | High cholesterol | 4 labelers | $2.88 per tablet 80 mg tablet | No | A presentation being discontinued |
| Gemfibrozilperoxisome proliferator receptor alpha agonist | Heart attack and coronary artery disease, High cholesterol | 27 labelers | $0.104 per tablet 600 mg tablet | Yes | A presentation being discontinued |
| Niacinnicotinic acid | Heart attack and coronary artery disease, High cholesterol, High triglycerides | 13 labelers | $0.193 per tablet 500 mg tablet | No | No current entry |
| Canagliflozinsodium-glucose cotransporter 2 inhibitor | Heart attack and coronary artery disease | none listed | $19.13 per tablet 100 mg tablet | No | No current entry |
| Bempedoic acidadenosine triphosphate-citrate lyase inhibitor | Heart attack and coronary artery disease, High cholesterol | none listed | $13.81 per tablet 180 mg tablet | No | No current entry |
| Bempedoic acid and ezetimibeadenosine triphosphate-citrate lyase inhibitor | Heart attack and coronary artery disease, High cholesterol | none listed | $13.80 per tablet 180-10 mg tablet | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Simvastatin: the full record
- label, generics, price, shortages, recalls
- Atorvastatin vs simvastatin
- two records side by side
- Simvastatin vs rosuvastatin
- two records side by side
- Pravastatin vs simvastatin
- two records side by side
- Lovastatin vs simvastatin
- two records side by side