Medicines labeled for the same conditions
Alternatives to roflumilast
3 other medicines are given the same way (oral) and in the same FDA class as roflumilast or labeled mainly for the same use (COPD); 1 is in its class, phosphodiesterase 4 inhibitors: apremilast; the others include 2 anticholinergics (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $90.57 per Otezla 30 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as roflumilast?
COPD lists all 23 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Roflumilastphosphodiesterase 4 inhibitor | this medicine | 16 labelers | $0.311 per tablet 500 mcg tablet | No | No current entry |
| Apremilastphosphodiesterase 4 inhibitor · same class | Psoriasis | none listed | $90.57 per tablet 30 mg tablet | No | No current entry |
| Tiotropiumanticholinergic | COPD | 1 labeler | $11.81 per capsule 18 mcg capsule-inhaler | No | No current entry |
| Umeclidiniumanticholinergic | COPD | none listed | $7.35 per inhaler 62.5 mcg inhaler | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Roflumilast: the full record
- label, generics, price, shortages, recalls