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Medicines labeled for the same conditions

Alternatives to regorafenib

5 other medicines are given the same way (oral) and in the same FDA class as regorafenib or labeled mainly for the same use (colorectal cancer); 1 is in its class, kinase inhibitors: tucatinib; the others include 1 nucleoside metabolic inhibitor and 1 thymidine phosphorylase inhibitor (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as regorafenib?

Colorectal cancer lists all 23 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Regorafenibkinase inhibitorthis medicinenone listedn/aYesNo current entry
Tucatinibkinase inhibitor · same classColorectal cancernone listedn/aNoNo current entry
Capecitabinenucleoside metabolic inhibitorColorectal cancer18 labelers$0.456 per tablet 500 mg tabletYesNo current entry
FruquintinibColorectal cancernone listedn/aNoNo current entry
Tipiracil and trifluridinethymidine phosphorylase inhibitorColorectal cancernone listedn/aNoNo current entry
EncorafenibColorectal cancernone listedn/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Regorafenib: the full record
label, generics, price, shortages, recalls