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Medicines labeled for the same conditions

Alternatives to ponatinib

37 other medicines are given the same way (oral) and in the same FDA class as ponatinib or labeled mainly for the same use (leukemia, lymphoma and myeloma); 10 are in its class, kinase inhibitors: dasatinib, imatinib, nilotinib, bosutinib and 6 more; the others include 3 alkylating drugs, 3 nucleoside metabolic inhibitors and 2 thalidomide analogs (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.624 per imatinib mesylate 100 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as ponatinib?

The first 24 of the 37, the same class first. Leukemia, lymphoma and myeloma lists all 98 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Ponatinibkinase inhibitorthis medicinenone listedn/aYesNo current entry
Dasatinibkinase inhibitor · same classLeukemia, lymphoma and myeloma14 labelers$26.46 per tablet 100 mg tabletNoNo current entry
Imatinibkinase inhibitor · same classLeukemia, lymphoma and myeloma20 labelers$0.624 per tablet 100 mg tabletNoNo current entry
Nilotinibkinase inhibitor · same classLeukemia, lymphoma and myeloma6 labelersn/aYesNo current entry
Bosutinibkinase inhibitor · same classLeukemia, lymphoma and myeloma3 labelersn/aNoNo current entry
Ibrutinibkinase inhibitor · same classLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Acalabrutinibkinase inhibitor · same classLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Pirtobrutinibkinase inhibitor · same classLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Quizartinibkinase inhibitor · same classLeukemia, lymphoma and myelomanone listedn/aYesNo current entry
Zanubrutinibkinase inhibitor · same classLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Midostaurinkinase inhibitor · same classLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Lenalidomidethalidomide analogLeukemia, lymphoma and myeloma18 labelersn/aYesNo current entry
Pomalidomidethalidomide analogLeukemia, lymphoma and myeloma11 labelersn/aYesNo current entry
Arsenic trioxideLeukemia, lymphoma and myelomanone listedn/aYesA presentation being discontinued
HydroxyureaantimetaboliteLeukemia, lymphoma and myeloma10 labelers$0.184 per capsule 500 mg capsuleNoNo current entry
Cyclophosphamidealkylating drugLeukemia, lymphoma and myeloma4 labelers$1.67 per capsule 50 mg capsuleNoNo current entry
BexaroteneretinoidLeukemia, lymphoma and myeloma7 labelersn/aYesNo current entry
Mercaptopurinenucleoside metabolic inhibitorLeukemia, lymphoma and myeloma2 labelers$1.07 per tablet 50 mg tabletNoNo current entry
Selinexornuclear export inhibitorLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
SonrotoclaxLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
ThalidomideLeukemia, lymphoma and myelomanone listedn/aYesNo current entry
AsciminibLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Ixazomibproteasome inhibitorLeukemia, lymphoma and myelomanone listedn/aNoNo current entry
Revumenibmenin inhibitorLeukemia, lymphoma and myelomanone listedn/aYesNo current entry
Venetoclaxbcl-2 inhibitorLeukemia, lymphoma and myelomanone listedn/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Ponatinib: the full record
label, generics, price, shortages, recalls