Alternatives to plecanatide
1 same-class SPL records vs plecanatide - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Trulance
About plecanatide
Trulance is a medicine that helps adults with certain bowel problems. It helps your bowels move more regularly.
Used for: Trulance treats chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). CIC means you have ongoing constipation with no known cause. IBS-C means you have stomach pain and constipation.
1 Guanylate Cyclase-C Agonist peers (wide set)
plecanatide vs linaclotide · FAERS reaction fields
FAERS top-reaction field "Diarrhoea" shows the widest count spread between plecanatide and linaclotide in this extract (4,139-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | plecanatide | linaclotide |
|---|---|---|
| Diarrhoea | 363 | 4,502 |
| Nausea | 159 | 1,373 |
| Constipation | 152 | 1,862 |
| Fatigue | 106 | 1,111 |
| Abdominal Distension | 100 | 1,100 |
| Abdominal Pain Upper | 100 | 884 |
| Abdominal Pain | 96 | 1,009 |
| Headache | 96 | 982 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
plecanatide peer mix vs class inventory
Peer mix
0 OTC and 1 Rx SPL records in this peer set (1 total). Class inventory for Guanylate Cyclase-C Agonist: 2 drugs.
Frequently Asked Questions
What same-class SPL records sit beside plecanatide? ▼
Reading a wide Guanylate Cyclase-C Agonist peer set (1 records)
plecanatide (Trulance) sits in a wide Guanylate Cyclase-C Agonist peer set (1 of 1 class peers shown). Labeled indication field for plecanatide: Trulance treats chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C).
Top FAERS reaction fields for plecanatide total 1,354 reports across 10 reactions, set beside linaclotide. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for plecanatide: see also the generic vs brand label guide when reading Trulance SPL strings.
Read our methodology - how this data is sourced, computed, and verified.