Medicines labeled for the same conditions
Alternatives to phentermine and topiramate
6 other medicines are given the same way (oral) and in the same FDA class as phentermine and topiramate or labeled mainly for the same use (weight management); 3 are in its class, sympathomimetic amine anorectics: diethylpropion, phendimetrazine and benzphetamine; the others include 1 glp-1 receptor agonist, 1 intestinal lipase inhibitor and 1 aminoketone (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.132 per phendimetrazine 35 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as phentermine and topiramate?
Weight management lists all 12 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Phentermine and topiramatesympathomimetic amine anorectic | this medicine | 2 labelers | $3.06 per capsule 7.5-46 mg capsule | No | No current entry |
| Diethylpropionsympathomimetic amine anorectic · same class | Weight management | 13 labelers | $0.238 per tablet 25 mg tablet | No | No current entry |
| Phendimetrazinesympathomimetic amine anorectic · same class | Weight management | 11 labelers | $0.132 per tablet 35 mg tablet | No | No current entry |
| Benzphetaminesympathomimetic amine anorectic · same class | Weight management | 6 labelers | n/a | No | No current entry |
| OrforglipronGLP-1 receptor agonist | Weight management | none listed | $20.89 per tablet 0.8 mg tablet | Yes | No current entry |
| Orlistatintestinal lipase inhibitor | Weight management | none listed | $7.00 per capsule 120 mg capsule | No | No current entry |
| Bupropion and naltrexoneaminoketone | Weight management | none listed | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Phentermine and topiramate: the full record
- label, generics, price, shortages, recalls