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Medicines labeled for the same conditions

Alternatives to ospemifene

6 other medicines are given the same way (oral) and in the same FDA class as ospemifene or labeled mainly for the same use (menopause symptoms); the others include 4 estrogens and 1 neurokinin 3 receptor antagonist (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as ospemifene?

Menopause symptoms lists all 11 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Ospemifeneestrogen agonist/antagonistthis medicinenone listed$8.17 per tablet 60 mg tabletYesNo current entry
EstradiolestrogenMenopause symptoms21 labelers$0.0635 per tablet 1 mg tabletYesNo current entry
Estradiol and norethindroneestrogenMenopause symptoms7 labelers$0.802 per tablet 0.5-0.1 mg tabletYesNo current entry
Estrogens conjugatedestrogenMenopause symptoms1 labeler$5.47 per tablet 0.625 mg tabletYesNo current entry
Fezolinetantneurokinin 3 receptor antagonistMenopause symptomsnone listed$18.58 per tablet 45 mg tabletYesNo current entry
Drospirenone and estradiolestrogenMenopause symptomsnone listed$6.37 per tablet 0.25 mg-0.5 mg tabletYesNo current entry
ElinzanetantMenopause symptomsnone listed$9.97 per capsule 60 mg capsuleNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Ospemifene: the full record
label, generics, price, shortages, recalls