Alternatives to midazolam
FDA shortage status is active for midazolam; 4 same-class SPL records are listed below for registry comparison only.
Brand: Versed
midazolam class peers while FDA lists an active shortage
midazolam (Versed) is on an FDA shortage listing while 4 other Benzodiazepine SPL records remain in this registry peer set (class inventory 5). Labeled indication field for midazolam: Midazolam is used to sedate you before a surgery or procedure to help you relax and feel less anxious.
Top FAERS reaction fields for midazolam total 9,004 reports across 10 reactions, set beside alprazolam, clonazepam, diazepam. Counts are exposure-weighted submissions, not per-patient risk.
About midazolam
Midazolam is a medicine that makes you feel calm, relaxed, and sleepy. It can also cause you to forget things that happen while you are taking it.
Used for: Midazolam is used to sedate you before a surgery or procedure to help you relax and feel less anxious. It can also be used to help you feel calm during procedures like bronchoscopies or endoscopies. Midazolam can also be used to start general anesthesia before you get other medicines.
4 Benzodiazepine peers (wide set)
alprazolam
RxXanax
Alprazolam is used to treat generalized anxiety disorder (GAD) and panic disorder (PD) in adults. GAD involves excessive worry and tension, while PD causes sudden and intense episodes of fear. This medicine can help reduce these symptoms.
clonazepam
RxKlonopin
Clonazepam is used to treat certain seizure disorders, including Lennox-Gastaut syndrome, akinetic, and myoclonic seizures. It can also treat absence seizures when other medicines don't work. Clonazepam also treats panic disorder, which involves unexpected panic attacks and worry about having more attacks.
diazepam
RxValium
Diazepam can help manage anxiety disorders or provide short-term relief from anxiety symptoms. It can also relieve symptoms of alcohol withdrawal, such as shaking or agitation. Additionally, diazepam can help with muscle spasms and may be used with other medicines to treat seizures.
lorazepam
RxAtivan
Lorazepam is used to manage anxiety disorders. It can also provide short-term relief from anxiety symptoms or anxiety linked to depression. However, it is not for the stress of everyday life. Talk to your doctor regularly to see if you still need this medicine.
midazolam vs alprazolam & clonazepam · FAERS reaction fields
FAERS top-reaction field "Toxicity To Various Agents" shows the widest count spread between midazolam and alprazolam, clonazepam, diazepam in this extract (8,321-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | midazolam | alprazolam | clonazepam | diazepam |
|---|---|---|---|---|
| Seizure | 1,373 | - | - | - |
| Hypotension | 1,296 | - | - | - |
| Drug Interaction | 1,088 | - | - | 4,139 |
| Toxicity To Various Agents | 846 | 8,863 | 5,182 | 9,167 |
| Acute Kidney Injury | 845 | - | - | - |
| Pyrexia | 813 | - | - | - |
| Cardiac Arrest | 811 | - | - | - |
| Death | 689 | 6,889 | - | 3,921 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
midazolam shortage vs Benzodiazepine peer index
Shortage status
FDA shortage listing is active for midazolam (status: Current). Peer rows remain a registry index, not a switch guide.
Frequently Asked Questions
Does FDA list a shortage for midazolam while peers remain indexed? ▼
Registry note: Shortage listings and peer indexes are for registry orientation only. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for midazolam: see also the generic vs brand label guide when reading Versed SPL strings.
Read our methodology - how this data is sourced, computed, and verified.