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meclizine

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Brand names: Antivert, Bonine

Antihistamine / Antiemetic OTC

Meclizine is an antihistamine and antiemetic. It helps prevent and treat nausea, vomiting, and dizziness, especially from motion sickness.

Drug Pricing (NADAC)

Generic Price

$0.03/unit

Generic Available

Yes (6 manufacturers)

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

What it does

Meclizine treats nausea, vomiting, and dizziness.

Common side effects

Dizziness, Fatigue

Key warnings

There are no boxed warnings for meclizine.

How It Works

Meclizine works by blocking certain natural substances in your body. These substances, like histamine, can cause nausea and dizziness. By blocking them, meclizine helps reduce these symptoms.

How to Take It

Take meclizine one hour before you start traveling. Adults and children 12 years and older can take 1 to 2 tablets once a day. You can chew the tablets or swallow them whole with water. For children under 12, ask a doctor.

Pregnancy & Breastfeeding

Talk to your doctor if you are pregnant or breastfeeding before taking meclizine. It is important to weigh the benefits and risks with your doctor.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.

Storage

Store meclizine at room temperature, away from heat and moisture.

Side Effects (from patient reports)

Based on 10,652 FDA adverse event reports.

Feeling dizzy
1,569
Feeling sick to your stomach
1,350
Feeling tired
1,302
Head pain
1,010
Loose stool
989
General pain
985
Accidental fall
964
Difficulty breathing
852
Long-term kidney problem
839
Weakness
792

FDA Adverse Event Report Analysis

Detailed analysis of 15,616 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2004–2025.

Total Reports

15,616

Death-Related Reports

1,426

Hospitalization Reports

4,910

Top Indication

Product Used For Unknown Indication

Gender Distribution

Female 10,928 (74%)
Male 3,808 (26%)

Age Distribution

0–17 132
18–44 1,197
45–64 3,350
65–74 2,389
75+ 2,512

Most Reported Adverse Reactions (FAERS)

# Reaction Reports
1 DIZZINESS 1,570
2 NAUSEA 1,351
3 FATIGUE 1,303
4 HEADACHE 1,010
5 DIARRHOEA 991
6 PAIN 985
7 FALL 965
8 DYSPNOEA 851
9 CHRONIC KIDNEY DISEASE 839
10 ASTHENIA 793
11 DRUG INEFFECTIVE 736
12 VOMITING 691
13 RENAL FAILURE 639
14 ANXIETY 607
15 VERTIGO 606

Reactions in Death Reports

DEATH 530
COMPLETED SUICIDE 180
TOXICITY TO VARIOUS AGENTS 133
RENAL FAILURE 109
CHRONIC KIDNEY DISEASE 101
ACUTE KIDNEY INJURY 93
NAUSEA 78
PNEUMONIA 77
FALL 76
ASTHENIA 70

Reactions in Hospitalization Reports

DIZZINESS 560
FALL 560
NAUSEA 500
DYSPNOEA 410
PAIN 400
ASTHENIA 393
FATIGUE 388
DIARRHOEA 358
PNEUMONIA 356
VOMITING 333

Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation

Serious Warnings

There are no boxed warnings for meclizine.

Common Questions

What is meclizine used for?
Meclizine is used to prevent and treat nausea, vomiting, and dizziness, especially from motion sickness.
How long before travel should I take meclizine?
Take meclizine one hour before you start traveling.
Can children take meclizine?
Children 12 years and older can take 1 to 2 tablets once daily. For children under 12, ask a doctor.
Can I chew the tablets?
Yes, you can chew the tablets or swallow them whole with water.
What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose.
Are there any side effects?
Common side effects include dizziness and fatigue.
Can I take meclizine if I am pregnant?
Talk to your doctor if you are pregnant before taking meclizine.
How should I store meclizine?
Store meclizine at room temperature, away from heat and moisture.
Can I use meclizine for other conditions?
For other uses, consult your doctor.
Is meclizine the same as Dramamine?
Meclizine is similar to Dramamine, but they contain different active ingredients. Ask your doctor which is best for you.
What are the common side effects of meclizine?
The most commonly reported side effects of meclizine include Dizziness, Fatigue. Based on 10,652 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
What drug class is meclizine?
meclizine belongs to the Antihistamine / Antiemetic drug class. It is available over the counter (OTC). Meclizine treats nausea, vomiting, and dizziness.
Is meclizine safe during pregnancy?
Talk to your doctor if you are pregnant or breastfeeding before taking meclizine. It is important to weigh the benefits and risks with your doctor. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

Related Medications in Antihistamine / Antiemetic

Other drugs grouped near meclizine — same-class peers and common alternatives.

Compare meclizine vs azelastine side-by-side →

Medication Guides

Related Health & Safety Data

What the FDA Data Shows for meclizine

The FDA label for meclizine (sold under brand names such as Antivert, Bonine) classifies it as an over-the-counter product in the Antihistamine / Antiemetic class. Meclizine treats nausea, vomiting, and dizziness. Official labeling lists 2 commonly reported side effects, including Dizziness, Fatigue.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 10,652 voluntary reports. Interaction data is drawn directly from FDA-approved prescribing information. NADAC pricing from CMS shows a generic unit cost of $0.03.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: January 9, 2025

All federal data sources used on this page