Prescription medication · Nasal Corticosteroid

ciclesonide nasal

Name: ciclesonide nasal - FDA Drug Safety & Adverse Event Data
Creator: PlainMeds
License: https://creativecommons.org/publicdomain/zero/1.0/

Also sold as Omnaris, Zetonna. This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Compiled by PlainMeds Editorial, Drug Information Editorial Team

Data updated 2026-05-15

3
InteractionsFew interactions: $22.60
Brand price (NADAC)

ciclesonide nasal (Omnaris) is a prescription Nasal Corticosteroid. This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Omnaris Nasal Spray is a medicine that helps treat allergy symptoms in your nose. It contains a steroid that reduces inflammation.

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Drug Pricing (NADAC)

Brand Price

$22.60/unit

Generic Available

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

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What it does

This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Common side effects

Headache, Nosebleeds, Nasal passage inflammation

Key warnings

This medicine may cause nosebleeds or a Candida (fungal) infection in your nose.

The sections below are summarized in plain English from ciclesonide nasal's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.

How It Works

Omnaris contains ciclesonide, a type of steroid. It works by reducing inflammation in your nose. This helps to relieve allergy symptoms like stuffiness and runny nose.

How to Take It

Shake the bottle gently before each use. Before you use it for the first time, prime the pump by spraying it 8 times. If you haven't used it for 4 days, re-prime it with 1 spray. The usual dose is 2 sprays in each nostril, once a day.

This is a plain-language summary of ciclesonide nasal's FDA labeling, not individualized dosing advice. Ask a pharmacist or prescriber before changing how you take this medication.

Pregnancy & Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Omnaris will harm your unborn baby. Talk to your doctor if you are breastfeeding.

This is a plain-language summary of ciclesonide nasal's FDA labeling, not individualized advice. Ask a pharmacist or prescriber about pregnancy or breastfeeding on this medication.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

This is a plain-language summary of ciclesonide nasal's FDA labeling, not individualized advice. Ask a pharmacist or prescriber what to do about your specific missed dose.

Storage

Store at room temperature (77°F). Do not freeze. Keep out of reach of children.

Serious Warnings

This medicine may cause nosebleeds or a Candida (fungal) infection in your nose. It can also cause a hole in the wall between your nostrils, and slow wound healing in your nose. Tell your doctor if you have vision changes or a history of glaucoma or cataracts. This medicine may also hide symptoms of an infection, worsen existing infections, or slow growth in children.

Known Drug Interactions

minor ketoconazole

In a drug interaction study, co-administration of orally inhaled ciclesonide and oral ketoconazole, a potent inhibitor of cytochrome P450 3A4, increased the exposure (AUC) of des-ciclesonide by approximately 3.6-fold at steady state, while levels of ciclesonide remained unchanged.

Mechanism: Ketoconazole slows down the process of clearing the active medicine from your system. This results in much higher levels of the drug in your body.

What to do: Use this combination with caution. Your healthcare provider may need to check for signs of increased steroid exposure.

minor erythromycin

Erythromycin, a moderate inhibitor of cytochrome P450 3A4, had no effect on the pharmacokinetics of either des-ciclesonide or erythromycin following oral inhalation of ciclesonide [see Clinical Pharmacology ( 12.3 )] .

Mechanism: Studies show that erythromycin does not change the amount of medicine that stays in your body.

What to do: No dosage adjustments are necessary when using these two medications together.

minor ciclesonide

7 DRUG INTERACTIONS In vitro studies and clinical pharmacology studies suggested that des-ciclesonide has no potential for metabolic drug interactions or protein binding-based drug interactions [see Clinical Pharmacology ( 12.3 )] . In a drug interaction study, co-administration of orally inhaled ciclesonide and oral ketoconazole, a potent inhibitor of cytochrome P450 3A4, increased the exposure (AUC) of des-ciclesonide by approximately 3.6-fold at steady state, while levels of ciclesonide remained unchanged. Erythromycin, a moderate inhibitor of cytochrome P450 3A4, had no effect on the...

Mechanism: This drug does not seem to change how other medicines are broken down or carried in the blood.

What to do: You generally do not need to worry about this drug causing interactions with other medications.

This is a plain-language summary of interactions documented in FDA labeling, not individualized advice. Ask a pharmacist or prescriber before combining medications.

Common Questions

What should I do if I get a nosebleed?

Contact your doctor if nosebleeds are severe or frequent.

Can this medicine cause infections?

Yes, it may increase your risk of nasal fungal infections.

How long can I use this nasal spray?

Throw away the bottle after 120 sprays or 4 months after opening it, even if it is not empty.

Can this medicine affect my vision?

Yes, it may increase your risk of glaucoma or cataracts.

Can children use this medicine?

Yes, children 6 years and older can use it for seasonal allergies.

What if I have a cold?

Talk to your doctor before using Omnaris if you have an infection.

Can I use this after nasal surgery?

Avoid using this medicine if you have recent nasal ulcers, surgery, or trauma until it heals.

What does 'prime the pump' mean?

Priming the pump means pressing the sprayer several times until a fine mist comes out. This ensures you get the right dose.

Can I use this if I'm allergic to other nasal sprays?

You should not use this if you are allergic to ciclesonide or any of the other ingredients.

Does this interact with other medications?

Ketoconazole may increase the amount of ciclesonide in your body. Tell your doctor about all medicines you take.

What are the common side effects of ciclesonide nasal?

The most commonly reported side effects of ciclesonide nasal include Headache, Nosebleeds, Nasal passage inflammation, Ear pain, Throat pain. Always consult your healthcare provider about potential side effects.

Does ciclesonide nasal interact with other medications?

Yes, ciclesonide nasal has 3 known drug interactions. Notable interactions include ketoconazole, erythromycin, ciclesonide. Always inform your doctor about all medications you are taking.

What drug class is ciclesonide nasal?

ciclesonide nasal belongs to the Nasal Corticosteroid drug class. It requires a prescription (Rx). This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Is ciclesonide nasal safe during pregnancy?

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Omnaris will harm your unborn baby. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

Related Medications in Nasal Corticosteroid

Other drugs grouped near ciclesonide nasal - same-class peers and common alternatives.

azelastine

Astelin, Astepro

Azelastine nasal spray is an antihistamine medicine.