Prescription medication · Nasal Corticosteroid

ciclesonide nasal

Also sold as Omnaris, Zetonna. This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Data updated 2026-05-15

3
InteractionsFew interactions
$22.60
Brand price (NADAC)

ciclesonide nasal (Omnaris) is a prescription Nasal Corticosteroid. This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Omnaris Nasal Spray is a medicine that helps treat allergy symptoms in your nose. It contains a steroid that reduces inflammation.

Verify with FDA → · CMS NADAC pricing →

Drug Pricing (NADAC)

Brand Price

$22.60/unit

Generic Available

No

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

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What it does

This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.

Common side effects

Headache, Nosebleeds, Nasal passage inflammation

Key warnings

This medicine may cause nosebleeds or a Candida (fungal) infection in your nose.

The sections below are summarized in plain English from ciclesonide nasal's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.

How It Works

Omnaris contains ciclesonide, a type of steroid. It works by reducing inflammation in your nose. This helps to relieve allergy symptoms like stuffiness and runny nose.

Serious Warnings

This medicine may cause nosebleeds or a Candida (fungal) infection in your nose. It can also cause a hole in the wall between your nostrils, and slow wound healing in your nose. Tell your doctor if you have vision changes or a history of glaucoma or cataracts. This medicine may also hide symptoms of an infection, worsen existing infections, or slow growth in children.

Known Drug Interactions

minor ketoconazole

In a drug interaction study, co-administration of orally inhaled ciclesonide and oral ketoconazole, a potent inhibitor of cytochrome P450 3A4, increased the exposure (AUC) of des-ciclesonide by approximately 3.6-fold at steady state, while levels of ciclesonide remained unchanged.

Mechanism: Ketoconazole slows down the process of clearing the active medicine from your system. This results in much higher levels of the drug in your body.

minor erythromycin

Erythromycin, a moderate inhibitor of cytochrome P450 3A4, had no effect on the pharmacokinetics of either des-ciclesonide or erythromycin following oral inhalation of ciclesonide [see Clinical Pharmacology ( 12.3 )] .

Mechanism: Studies show that erythromycin does not change the amount of medicine that stays in your body.

minor ciclesonide

7 DRUG INTERACTIONS In vitro studies and clinical pharmacology studies suggested that des-ciclesonide has no potential for metabolic drug interactions or protein binding-based drug interactions [see Clinical Pharmacology ( 12.3 )] . In a drug interaction study, co-administration of orally inhaled ciclesonide and oral ketoconazole, a potent inhibitor of cytochrome P450 3A4, increased the exposure (AUC) of des-ciclesonide by approximately 3.6-fold at steady state, while levels of ciclesonide remained unchanged. Erythromycin, a moderate inhibitor of cytochrome P450 3A4, had no effect on the...

Mechanism: This drug does not seem to change how other medicines are broken down or carried in the blood.

This is a plain-language summary of FDA-label interaction records and does not provide individual medication-combination directions.

Common Questions

What should I do if I get a nosebleed?
Contact your doctor if nosebleeds are severe or frequent.
Can this medicine cause infections?
Yes, it may increase your risk of nasal fungal infections.
How long can I use this nasal spray?
Throw away the bottle after 120 sprays or 4 months after opening it, even if it is not empty.
Can this medicine affect my vision?
Yes, it may increase your risk of glaucoma or cataracts.
Can children use this medicine?
Yes, children 6 years and older can use it for seasonal allergies.
What if I have a cold?
Talk to your doctor before using Omnaris if you have an infection.
Can I use this after nasal surgery?
Avoid using this medicine if you have recent nasal ulcers, surgery, or trauma until it heals.
What does 'prime the pump' mean?
Priming the pump means pressing the sprayer several times until a fine mist comes out. This ensures you get the right dose.
Can I use this if I'm allergic to other nasal sprays?
You should not use this if you are allergic to ciclesonide or any of the other ingredients.
Does this interact with other medications?
Ketoconazole may increase the amount of ciclesonide in your body. Tell your doctor about all medicines you take.
What are the common side effects of ciclesonide nasal?
The registry lists Headache, Nosebleeds, Nasal passage inflammation, Ear pain, Throat pain among the most-reported FAERS reaction terms for ciclesonide nasal. These counts are not an individual symptom assessment.
Does ciclesonide nasal interact with other medications?
The registry has 3 documented interaction rows for ciclesonide nasal. Notable source-record pairings include ketoconazole, erythromycin, ciclesonide. These rows are not a complete medication review.
What drug class is ciclesonide nasal?
ciclesonide nasal belongs to the Nasal Corticosteroid drug class. It requires a prescription (Rx). This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older.
What pregnancy or breastfeeding source fields are listed for ciclesonide nasal?
The FDA label for ciclesonide nasal contains product-specific pregnancy or breastfeeding language. PlainMeds does not apply that source text to an individual.

Related Medications in Nasal Corticosteroid

Other drugs grouped near ciclesonide nasal - same-class peers and common alternatives.

azelastine

Astelin, Astepro

Azelastine nasal spray is an antihistamine medicine.

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budesonide nasal

Rhinocort

Rhinocort is a nasal spray that helps relieve allergy symptoms.

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cetirizine

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Cetirizine (Zyrtec) is an antihistamine medicine.

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chlorpheniramine

Chlor-Trimeton

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desloratadine

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What the FDA Data Shows for ciclesonide nasal

The FDA label for ciclesonide nasal (sold under brand names such as Omnaris, Zetonna) classifies it as a prescription-only medication in the Nasal Corticosteroid class. This medicine treats nasal symptoms from seasonal allergies in adults and kids 6 years and older. Official labeling lists 5 commonly reported side effects, including Headache, Nosebleeds, Nasal passage inflammation.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. The database also lists 3 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. NADAC pricing from CMS.

Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.

Last updated: November 8, 2022

PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.

Read our methodology - how this data is sourced, computed, and verified.

Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.

All federal data sources used on this page