Alternatives to letrozole
1 same-class SPL records vs letrozole - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Femara
How to read a high-report FAERS peer set
letrozole ranks in the upper FAERS-volume third of the corpus (#123 of 524); 1 same-class peers are listed for field comparison only. Labeled indication field for letrozole: Letrozole is used to treat breast cancer in women who have gone through menopause.
Top FAERS reaction fields for letrozole total 42,902 reports across 10 reactions, set beside anastrozole. Counts are exposure-weighted submissions, not per-patient risk.
About letrozole
Letrozole is a medicine that lowers estrogen levels in women after menopause. It is used to treat breast cancer that is affected by hormones.
Used for: Letrozole is used to treat breast cancer in women who have gone through menopause. It can be used as an initial treatment, after other treatments like tamoxifen, or when the cancer has spread. It works best for cancers that are hormone receptor positive or when the hormone receptor status is unknown.
1 Aromatase Inhibitor peers (wide set)
letrozole vs anastrozole · FAERS reaction fields
FAERS top-reaction field "Neutropenia" shows the widest count spread between letrozole and anastrozole in this extract (4,896-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | letrozole | anastrozole |
|---|---|---|
| Fatigue | 7,159 | 3,256 |
| Nausea | 5,259 | 2,648 |
| Neutropenia | 4,896 | - |
| Diarrhoea | 4,460 | 2,267 |
| Malignant Neoplasm Progression | 4,254 | 1,313 |
| Arthralgia | 3,803 | 3,158 |
| White Blood Cell Count Decreased | 3,678 | - |
| Alopecia | 3,582 | 2,537 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
letrozole FAERS volume vs class peers
FAERS volume band
letrozole is FAERS corpus rank #123 of 524 (high volume tercile). Top-reaction field total: 42,902.
Frequently Asked Questions
Where does letrozole sit in FAERS report volume vs Aromatase Inhibitor peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for letrozole: see also the generic vs brand label guide when reading Femara SPL strings.
Read our methodology - how this data is sourced, computed, and verified.