Medicines labeled for the same conditions
Alternatives to irinotecan
8 other medicines are given the same way (intravenous) and in the same FDA class as irinotecan or labeled mainly for the same use (colorectal cancer); the others include 3 vascular endothelial growth factor inhibitors, 2 epidermal growth factor receptor antagonists and 1 platinum-based drug (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as irinotecan?
Colorectal cancer lists all 23 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (intravenous) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Irinotecantopoisomerase inhibitor | this medicine | 12 labelers | n/a | Yes | A presentation being discontinued |
| Oxaliplatinplatinum-based drug | Colorectal cancer | 17 labelers | n/a | Yes | A presentation being discontinued |
| Fluorouracilnucleoside metabolic inhibitor | Colorectal cancer | 12 labelers | n/a | Yes | No current entry |
| Levoleucovorinfolate analog | Colorectal cancer | 8 labelers | n/a | No | No current entry |
| Bevacizumabvascular endothelial growth factor inhibitor | Colorectal cancer | none listed | n/a | No | No current entry |
| Afliberceptvascular endothelial growth factor inhibitor | Colorectal cancer | none listed | n/a | No | No current entry |
| Bevacizumab-malyvascular endothelial growth factor inhibitor | Colorectal cancer | none listed | n/a | No | No current entry |
| Cetuximabepidermal growth factor receptor antagonist | Colorectal cancer | none listed | n/a | Yes | No current entry |
| Panitumumabepidermal growth factor receptor antagonist | Colorectal cancer | none listed | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Irinotecan: the full record
- label, generics, price, shortages, recalls
- Irinotecan vs oxaliplatin
- two records side by side