Alternatives to glyburide
FDA shortage status is active for glyburide; 2 same-class SPL records are listed below for registry comparison only.
Brand: DiaBeta, Glynase
glyburide class peers while FDA lists an active shortage
glyburide (DiaBeta, Glynase) is on an FDA shortage listing while 2 other Sulfonylurea SPL records remain in this registry peer set (class inventory 3). Labeled indication field for glyburide: Glyburide is used to help control blood sugar levels in adults who have type 2 diabetes.
Top FAERS reaction fields for glyburide total 14,700 reports across 10 reactions, set beside glimepiride, glipizide. Counts are exposure-weighted submissions, not per-patient risk.
About glyburide
Glyburide is a medicine that helps lower blood sugar in adults with type 2 diabetes. It works along with diet and exercise.
Used for: Glyburide is used to help control blood sugar levels in adults who have type 2 diabetes. It is prescribed in addition to diet and exercise. This medicine helps your body use insulin better, which lowers your blood sugar.
2 Sulfonylurea peers (wide set)
glimepiride
RxAmaryl
Glimepiride is used to help control blood sugar levels in adults with type 2 diabetes. It should be used with a healthy diet and regular exercise. This medicine will not work for type 1 diabetes or diabetic ketoacidosis.
glipizide
RxGlucotrol
Glipizide is used to improve blood sugar control in adults who have type 2 diabetes. It is meant to be used in addition to diet and exercise. This medicine helps your body use insulin better and lowers blood sugar levels.
glyburide vs glimepiride & glipizide · FAERS reaction fields
FAERS top-reaction field "Blood Glucose Increased" shows the widest count spread between glyburide and glimepiride, glipizide in this extract (3,639-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | glyburide | glimepiride | glipizide |
|---|---|---|---|
| Blood Glucose Increased | 3,038 | 2,970 | 6,677 |
| Nausea | 2,019 | 2,276 | 4,444 |
| Weight Decreased | 1,537 | 1,391 | 2,812 |
| Diarrhoea | 1,282 | 2,169 | 3,265 |
| Dizziness | 1,201 | 1,365 | 2,438 |
| Hypoglycaemia | 1,171 | 1,639 | - |
| Blood Glucose Decreased | 1,163 | - | 2,232 |
| Fatigue | 1,147 | 1,827 | 2,994 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
glyburide shortage vs Sulfonylurea peer index
Shortage status
FDA shortage listing is active for glyburide (status: To Be Discontinued). Peer rows remain a registry index, not a switch guide.
Frequently Asked Questions
Does FDA list a shortage for glyburide while peers remain indexed? ▼
Registry note: Shortage listings and peer indexes are for registry orientation only. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for glyburide: see also the generic vs brand label guide when reading DiaBeta SPL strings.
Read our methodology - how this data is sourced, computed, and verified.