FDA data Registry peer set 5 peers

Alternatives to fluoxetine

5 same-class SPL records vs fluoxetine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.

View fluoxetine → All alternatives

Brand: Prozac, Sarafem

Selective Serotonin Reuptake Inhibitor (SSRI) Prescription 5 alternatives found

How to read a high-report FAERS peer set

fluoxetine ranks in the upper FAERS-volume third of the corpus (#114 of 524); 5 same-class peers are listed for field comparison only. Labeled indication field for fluoxetine: Fluoxetine can treat major depressive disorder in adults and children.

Top FAERS reaction fields for fluoxetine total 28,206 reports across 10 reactions, set beside citalopram, escitalopram, fluvoxamine. Counts are exposure-weighted submissions, not per-patient risk.

About fluoxetine

Fluoxetine is a medicine that can help treat depression and other mental health conditions. It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs).

Used for: Fluoxetine can treat major depressive disorder in adults and children. It also treats obsessive-compulsive disorder (OCD) in adults and children. Fluoxetine can help with bulimia nervosa (an eating disorder) and panic disorder. Sometimes, it is used with another medicine called olanzapine to treat depression related to bipolar disorder.

View full fluoxetine profile →

5 Selective Serotonin Reuptake Inhibitor (SSRI) peers (wide set)

citalopram

Rx

Celexa

Citalopram is used to treat major depressive disorder (MDD) in adults. Depression can cause feelings of sadness, loss of interest, and difficulty functioning in daily life. This medicine can help improve your mood and overall well-being.

escitalopram

Rx

Lexapro

Escitalopram is used to treat major depressive disorder (MDD) in adults and children 12 years and older. It also treats generalized anxiety disorder (GAD) in adults. This medicine can help improve your mood and reduce feelings of worry.

fluvoxamine

Rx

Luvox

Fluvoxamine is used to treat obsessive compulsive disorder (OCD). OCD involves having constant, unwanted thoughts or behaviors that you feel the need to repeat. These thoughts or actions can cause you distress and interfere with your daily life.

paroxetine

Rx

Paxil

Paroxetine is used to treat several conditions in adults. These include major depressive disorder (MDD), obsessive compulsive disorder (OCD), panic disorder (PD), social anxiety disorder (SAD), generalized anxiety disorder (GAD), and posttraumatic stress disorder (PTSD). It helps to improve mood and reduce anxiety and panic feelings.

sertraline

Rx

Zoloft

Sertraline is used to treat major depressive disorder in adults. This means it can help with ongoing sadness or loss of interest in things. It also treats obsessive-compulsive disorder (OCD), where you have unwanted thoughts or behaviors that you can't control. Sertraline can also treat panic disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder.

Compare fluoxetine vs citalopram side-by-side →

fluoxetine vs citalopram & escitalopram · FAERS reaction fields

FAERS top-reaction field "Fatigue" shows the widest count spread between fluoxetine and citalopram, escitalopram, fluvoxamine in this extract (6,040-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.

Side Effect fluoxetine citalopramescitalopramfluvoxamine
Drug Interaction 3,335 4,348 3,707 215
Toxicity To Various Agents 3,316 5,061 - 70
Nausea 3,233 8,210 9,164 117
Fatigue 3,156 8,930 9,196 86
Completed Suicide 2,904 4,338 - 69
Headache 2,774 6,656 7,114 86
Anxiety 2,444 5,436 6,447 103
Diarrhoea 2,374 6,218 6,709 -

"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.

fluoxetine FAERS volume vs class peers

FAERS volume band

fluoxetine is FAERS corpus rank #114 of 524 (high volume tercile). Top-reaction field total: 28,206.

Frequently Asked Questions

Where does fluoxetine sit in FAERS report volume vs Selective Serotonin Reuptake Inhibitor (SSRI) peers? ▼
fluoxetine ranks #114 of 524 drugs by FAERS top-reaction report volume (high volume tercile). Top-reaction fields total 28,206 submissions in this extract, exposure-weighted counts, not per-patient risk.

Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.

Full fluoxetine profile →

Field note for fluoxetine: see also the generic vs brand label guide when reading Prozac SPL strings.

Read our methodology - how this data is sourced, computed, and verified.